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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGKZ All Species: 17.58
Human Site: S1072 Identified Species: 29.74
UniProt: Q13574 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13574 NP_001099010.1 1117 124128 S1072 Y I V E A G A S L M K T D Q Q
Chimpanzee Pan troglodytes XP_508395 1117 124129 S1072 Y I V E A G A S L M K T D Q Q
Rhesus Macaque Macaca mulatta XP_001102461 1084 120447 S1039 Y I V E A G A S L M K T D Q Q
Dog Lupus familis XP_540755 766 85714 G722 Q K R V P Q V G F L D A T T A
Cat Felis silvestris
Mouse Mus musculus Q80UP3 929 104029 L885 I V E A G A S L M K T D L Q G
Rat Rattus norvegicus O08560 929 103991 L885 I V E A G A S L M K T D Q Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513139 955 107141 L911 L V D A G A S L R K M D S E G
Chicken Gallus gallus NP_001026363 953 106222 L909 I V E A G A S L M K T D L Q G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922445 1086 121319 S1026 Y L V E A G A S L M K T D L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q09103 1457 160124 T1392 A D K E L G Q T A L H I A A E
Honey Bee Apis mellifera XP_396522 837 92900 T793 M L V A G G A T L I I K D R H
Nematode Worm Caenorhab. elegans Q10024 937 105180 A893 P S I T D R E A V E L F Q P Q
Sea Urchin Strong. purpuratus XP_796061 815 92455 L771 R R T I C A M L V E A G A A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39017 728 79965 K684 H G Q A F M L K R A A E E P L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 90.3 65.1 N.A. 78.2 79.3 N.A. 54.7 67.8 N.A. 60.4 N.A. 31.9 31.2 31.6 43.1
Protein Similarity: 100 99.8 91.2 66.6 N.A. 80.5 80.5 N.A. 65.8 74.8 N.A. 70.6 N.A. 46.1 46.2 46.3 55
P-Site Identity: 100 100 100 0 N.A. 6.6 6.6 N.A. 0 6.6 N.A. 86.6 N.A. 13.3 33.3 6.6 0
P-Site Similarity: 100 100 100 6.6 N.A. 26.6 26.6 N.A. 20 26.6 N.A. 93.3 N.A. 33.3 60 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 32.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 43 29 36 36 8 8 8 15 8 15 15 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 8 0 0 0 0 0 8 29 36 0 0 % D
% Glu: 0 0 22 36 0 0 8 0 0 15 0 8 8 8 8 % E
% Phe: 0 0 0 0 8 0 0 0 8 0 0 8 0 0 0 % F
% Gly: 0 8 0 0 36 43 0 8 0 0 0 8 0 0 29 % G
% His: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % H
% Ile: 22 22 8 8 0 0 0 0 0 8 8 8 0 0 0 % I
% Lys: 0 8 8 0 0 0 0 8 0 29 29 8 0 0 0 % K
% Leu: 8 15 0 0 8 0 8 36 36 15 8 0 15 8 15 % L
% Met: 8 0 0 0 0 8 8 0 22 29 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 8 0 0 0 0 0 0 0 0 15 0 % P
% Gln: 8 0 8 0 0 8 8 0 0 0 0 0 15 43 36 % Q
% Arg: 8 8 8 0 0 8 0 0 15 0 0 0 0 8 0 % R
% Ser: 0 8 0 0 0 0 29 29 0 0 0 0 8 0 0 % S
% Thr: 0 0 8 8 0 0 0 15 0 0 22 29 8 8 0 % T
% Val: 0 29 36 8 0 0 8 0 15 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 29 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _